does replacement pancreatic enzymes affect lipase levels?

5 Apr

HEADLINE:
–According to the study below (even though its in pigs), being on replacement enzymes shouldn’t affect your lipase levels

PMID: 14707735
–The enzyme levels in blood are not affected by oral administration of a pancreatic enzyme preparation (Creon 10,000) in pancreas-insufficient pigs.


–The current study investigated whether orally administered pancreatic enzymes were absorbed from the intestine.
 
–28 pigs; 3 control pigs with intact pancreatic function and 25 pigs that were made exocrine pancreas insufficient by duct ligation (20 pigs) or total pancreatectomy (5 pigs).
–pigs received a pancreatic enzyme preparation (0, 2, 4, or 8 g of Creon 10,000) together with the feed. The blood plasma was analyzed for pancreatic lipase activity.

–Administration of Creon (0–8 g) caused no significant changes in plasma (pro)colipase or cationic trypsin(ogen) levels.

BOTTOM LINE:
–According to the study below (even though its in pigs), being on replacement enzymes shouldn’t affect your lipase levels

Submitted by J. Gullo.

Reference(s): article, picture

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