atypical antipsychotic receptors: nice tiny chart

21 Dec

Nice brief chart in November’s EMN (along with an article) in November’s Emergency Medicine News:

CLICK THROUGH TO THE ARTICLE TO SEE THE CHART:

 

10-SECOND TAKEAWAY:

atypical antipsychotics include:

  • olanzapine (zyprexa)
  • quetiapine (seroquel)
  • clozapine (clozaril)
  • aripiprazole (abilify)
  • risperidone (risperidal)
  • ziprasidone (geodon)

 

these tend to have multiple receptor affinities (antagonists of:

 

BOTTOM LINE:

not all antipsychotics hit all these receptors, but in OD, likely to be:

  • tachy(cardic)
  • wacky(CNS effects)

 

  • if there’s alpha-effects, hypotension
  • worst case, as with most tox end-points: seizure/coma/death.

 

References: article; picture

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: