treating GI bleeding in cirrhotics

21 Feb

nice NNT breakdown in February’s EPmonthly


prophylactic antibiotics for cirrhotic GI bleeders:

  • NNT (to prevent 1 infection) = 4
  • NNT (to prevent 1 death) = 22
  • WHY:
    • cirrhotics have impaired immune function and increased bowel translocation of bacteria
    • give antibiotics during bleeding event to help prevent infections


octreotide (somatostatin analogue) for variceal bleeding:

  • NNT: no benefit


References: epmonthly article; picture


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