treating GI bleeding in cirrhotics

21 Feb

nice NNT breakdown in February’s EPmonthly

10-SECOND TAKEAWAY:

prophylactic antibiotics for cirrhotic GI bleeders:

  • NNT (to prevent 1 infection) = 4
  • NNT (to prevent 1 death) = 22
  • WHY:
    • cirrhotics have impaired immune function and increased bowel translocation of bacteria
    • give antibiotics during bleeding event to help prevent infections

 

octreotide (somatostatin analogue) for variceal bleeding:

  • NNT: no benefit

 

References: epmonthly article; picture

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