Kawasaki Disease (30-second review)

20 Jun

Sensitivity of physical exam findings:

Fever x 5 days plus at least 4/5 of:

1. Conjunctival injection (bilateral)

2. MM changes (eg. Fissured lips, strawberry tongue)

3. Polymorphous rash

4. Extremity changes (edema, desquamation)

5. Cervical LAD

 Sensitivity 90%, specificity 54%

 

20-25% develop coronary aneurysms, typically clinically silent until sudden death

 

IVIG reduces aneurysms to only 2-4% cases

 

MIMICKERS – GAS pharyngitis (scarlet fever), measles

 

Med-school mnemonic: CRASH & BURN

  • Conjunctivitis
  • Rash
  • Adenopathy/Aneurysm
  • Strawberry tongue
  • Hand/foot induration/desquamation

&

  • BURN – fever x 5 days

 

 

Submitted by J. Andrick.

 

References: Kawasaki Syndrome, Burns, Glode review Lancet 2004; Kawasaki Disease II Yim et al. J Ped Child Health.; picture

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: