nebulized naloxone

18 Nov

Nice review in November’s EP Monthly mag by Drs. Hepker & Erickson:

HIGHLIGHTS:

DOSING:

2 mg nalaxone + 3 mL normal saline

placed in standard canister, nebulize away

REMEMBER: repeated or continuous nebs may be needed (half-life of Narcan much less than opiods)

 

SUPPORT:

  • 105 case study
    • 23% complete response
    • 59% partial response
    • 19% no response
    • no adverse events, no assisted ventilation
  • 26 patient study
    • mean GCS improved from 11 to 13
    • mean RASS improved from -3 to -2

 

DOSING (reminder):

2 mg nalaxone + 3 mL normal saline

 

References: epmonthly.com; picture

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